FREQUENTLY ASKED

Everything you might ask, in one place.

Forty answers covering everything from how Hawaiian astaxanthin actually works to how to pause your subscription. Use the search bar to jump straight to a topic, or the category nav to browse.

Product & Science

What's actually in the bottle, and what the science says.

What is astaxanthin?

Astaxanthin is a naturally occurring carotenoid — the same family of pigments that give carrots their orange and salmon their pink. It's produced in nature by a microscopic freshwater algae called Haematococcus pluvialis, which generates astaxanthin as a defence against intense sunlight and oxidative stress.

What makes astaxanthin different from other antioxidants is its molecular structure: it's one of the few that crosses both the blood-retinal barrier and the blood-brain barrier, meaning it can act directly inside the cells of the eye and brain rather than just circulating in the bloodstream. It's also able to span the entire cell membrane, protecting both the water-soluble inside and the fat-soluble outside layer.

Crocea is a single-ingredient supplement: 12 mg of Hawaiian-sourced natural astaxanthin in a cold-pressed coconut oil softgel. Nothing else.

Why specifically Hawaiian astaxanthin?

Two reasons — purity and potency.

Purity: the Big Island of Hawaii has an ideal climate (intense year-round sunlight) and clean, lava-filtered aquifer water, with strict US agricultural standards. The result is a pristine growing environment with minimal heavy-metal exposure compared to open-ocean or industrial-area aquaculture.

Potency: the algae are grown outdoors under direct Hawaiian sunlight, which forces the Haematococcus pluvialis to produce astaxanthin as a survival mechanism. More stress = more astaxanthin per cell. The 3S,3'S stereoisomer profile (the molecular orientation) produced by sun-grown Hawaiian algae is the same one studied in the clinical trials — and is up to 20–30× more biologically active than the synthetic version used in many cheap supplements.

Why 12 mg specifically? Isn't more better?

12 mg is the dose used in the majority of positive human clinical trials on astaxanthin — for eye fatigue, visual comfort, skin elasticity, and antioxidant defence. It's the dose where benefits become measurable while staying well within the EFSA-established safety range (the European Food Safety Authority set the Acceptable Daily Intake at 0.2 mg per kg body weight, meaning a 70 kg / 154 lb adult can safely take up to 14 mg/day).

Doses above 12 mg don't appear to produce a meaningfully larger benefit for eye health in the published research. We chose 12 mg because it's the highest dose with the strongest supporting evidence — not the highest dose we could legally print on a label.

Is Crocea vegan / vegetarian?

The astaxanthin itself is algae-derived, so it's plant-based.

Our softgel is made from fish-free, gelatin-free vegetable cellulose with glycerin, so the product as a whole is suitable for vegetarians. The cold-pressed carrier oil is coconut. There are no animal-derived ingredients anywhere in the formula.

For strict vegans: the softgel material is plant-based. We do not test on animals.

What's NOT in Crocea?

Single ingredient + carrier oil. That's it. We don't add:

  • Fillers (no maltodextrin, no cellulose padding, no rice flour)
  • Synthetic dyes or colourings
  • Caffeine or stimulants
  • Proprietary blends (the dose of every active is on the label)
  • Gluten, soy, dairy, eggs, nuts, peanuts
  • GMO ingredients
  • Sugar or sweeteners

The full Supplement Facts panel is on every bottle and on the product page. If you have a specific allergen concern not listed here, email support@trycrocea.com with your concern and we'll send you the most recent Certificate of Analysis.

Eye Health & Benefits

What Crocea supports — written honestly, within the limits of what dietary supplements can claim.

What does Crocea actually support for eye health?

Based on the published clinical research on astaxanthin at the 6–12 mg dose, the evidence is strongest for:

  • Visual comfort during prolonged screen use — supporting healthy accommodation (the focusing muscle), reducing subjective eye-strain symptoms
  • Sustained focus / near-vision comfort — particularly for adults 40+ experiencing presbyopia-related strain
  • Macular blood flow — supporting normal circulation in the small vessels that feed the central retina
  • Tear film stability — supporting comfort for people with mild dryness and gritty-feeling eyes
  • Antioxidant defence inside the eye — astaxanthin reaches cells that lutein and zeaxanthin do not

What Crocea is not: a treatment, a cure, or a prevention for any eye disease. It's a dietary supplement that supports the normal antioxidant defences of your eyes and visual system. If you have a diagnosed eye condition, please talk to your ophthalmologist before adding any new supplement.

Will Crocea cure my macular degeneration / cataracts / glaucoma?

No. Dietary supplements cannot treat, cure, or prevent any disease — that's not a marketing position, that's US federal law (DSHEA, 1994) and a hard line we won't cross.

If you have a diagnosed eye condition like macular degeneration, cataracts, or glaucoma, your ophthalmologist is the right person to talk to. Your doctor may recommend the AREDS2 formulation specifically for AMD, prescription medication for glaucoma, or surgical evaluation for cataracts.

What we can honestly say: astaxanthin is a well-studied antioxidant that supports the normal antioxidant defences of the eye. Many customers with family histories of AMD take Crocea as part of a broader eye-health routine — but always alongside their doctor's recommendations, never instead of them.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

How long until I notice a difference?

Individual results vary, but the typical timeline based on the clinical research is:

  • 2–4 weeks: earliest changes — most often reduced eye-strain symptoms and improved comfort during long screen use. About a third of customers report something around this window.
  • 8–12 weeks: larger group reports noticeable improvements — sharper contrast, better night-driving comfort, less squinting.
  • 3–6 months: astaxanthin reaches steady-state concentration in retinal tissue. This is when sustained benefits accumulate.
  • Ongoing: consistent daily use is what the studies measured. Astaxanthin is fat-soluble and accumulates with daily intake; results aren't from a single dose, they're from sustained levels.

If you don't notice anything by week 6 of consistent daily use, your 30-Day Satisfaction Guarantee window has already passed — but email us anyway. Some people are slow responders, some have other factors at play, and sometimes we just need to talk through what "better" looks like for you.

How is Crocea different from lutein or AREDS2?

They work in different places and complement each other.

Lutein and zeaxanthin (the carotenoids in AREDS2 and most eye multis) accumulate in the macular pigment at the centre of the retina and act primarily as blue-light filters and macular protection. Best evidence is for slowing AMD progression in people with established intermediate AMD.

Astaxanthin works inside retinal cells, in the ciliary body (the focusing muscle), in the aqueous humour of the front of the eye, and supports macular blood flow. Best evidence is for visual comfort, accommodation/focus, and tear-film stability.

One isn't a replacement for the other. If you've been told by an ophthalmologist to take AREDS2 for diagnosed AMD, keep taking it — astaxanthin is a complementary antioxidant, not a substitute for the AREDS protocol.

Will Crocea help if I work on a screen all day?

That's actually one of the strongest evidence territories for astaxanthin. Multiple controlled trials in office workers and screen-heavy populations have shown improvement in subjective eye-strain symptoms (the feeling of tired, achey, dry eyes after a long day) and in objective measures of accommodation (how easily the eye refocuses from screen to distance).

The mechanism: astaxanthin appears to support the ciliary muscle (the small muscle that changes the shape of your lens to focus) and to support tear-film stability. Both are stressed by hours of fixed-distance staring at a screen.

Practical note: Crocea is a supplement, not a substitute for good screen habits. The 20-20-20 rule (every 20 minutes, look 20 feet away for 20 seconds), proper screen height, blue-light reduction at night, and adequate sleep all matter alongside any supplement.

How to Take Crocea

Dose, timing, and getting the most out of every softgel.

How many softgels per day?

One softgel daily with food. That delivers the full 12 mg clinical dose. There's no benefit to taking more.

The bottle contains 30 softgels — a one-month supply. Take it consistently every day; astaxanthin is fat-soluble and builds up in tissue over weeks of daily intake, which is what produces the benefits seen in studies.

With food or on an empty stomach?

With food — ideally a meal that contains some healthy fat (avocado, olive oil, eggs, nuts, salmon).

Astaxanthin is a fat-soluble carotenoid. Its absorption is dramatically improved by the presence of dietary fat in the same meal. Crocea is already formulated in a cold-pressed coconut oil softgel to give it a lipid carrier — but eating it with a meal multiplies absorption further.

Taking it on an empty stomach won't hurt you, but you'll get significantly less of the active ingredient into your bloodstream.

Best time of day to take it?

Whenever you'll actually remember to do it — consistency matters more than time of day.

That said, most customers take Crocea with breakfast (highest-fat meal of the day for many people, and easier to remember). Some take it with dinner. Both work.

Astaxanthin doesn't stimulate, doesn't sedate, and doesn't affect sleep. So time of day is purely about your routine.

I missed a day — should I double up the next day?

No, just take one softgel the next day as usual.

Astaxanthin's benefits come from steady-state tissue concentrations built up over weeks of daily use, not from a peak dose on any single day. Doubling up doesn't "catch up" and exceeds the dose that the clinical studies measured.

If you frequently forget, set a phone alarm or leave the bottle next to your coffee maker. Consistency is the single biggest factor in whether a supplement works.

Should I take a break from Crocea, or cycle it?

The clinical studies on astaxanthin used continuous daily dosing — no cycling — for periods of 8 weeks to 6 months, with safety established at much longer use. There's no published evidence that cycling produces a benefit or that continuous use produces tolerance or downregulation.

So: no need to cycle. Take it daily, and re-evaluate every 6–12 months whether you're still noticing the benefit. The 30-day Satisfaction Guarantee on your first order is our recommended trial window — by the end of 30–60 days you'll have a pretty clear sense of whether it's working for you.

Safety & Interactions

Important answers if you're on medication, pregnant, or planning surgery.

Are there any side effects?

Astaxanthin is exceptionally well-tolerated. The European Food Safety Authority reviewed the safety data in 2020 and established an Acceptable Daily Intake of 0.2 mg/kg body weight — well above the 12 mg dose in Crocea for any adult.

Rare, mild effects sometimes reported in the literature: a slight orange-pink tint to the skin at very high doses (much higher than 12 mg), mild digestive sensitivity if taken on a completely empty stomach (avoid this by taking with food), or rarely a slight increase in libido (also reported as a positive).

If you experience anything unusual, stop taking the product and email support@trycrocea.com. If symptoms are severe or persistent, contact your doctor.

Can I take Crocea with prescription medications?

For most medications, astaxanthin has no known clinically significant interaction. It's been used in clinical trials in populations on common medications without issues reported.

However, we are not your doctor or pharmacist. We strongly recommend talking to your healthcare provider before adding any new supplement, especially if you take:

  • Blood thinners (warfarin, apixaban, rivaroxaban) — astaxanthin may have mild antiplatelet effects; your doctor needs to weigh this
  • Diabetes medications (potential effect on insulin sensitivity)
  • Immunosuppressants
  • Multiple chronic medications

Bring the supplement facts panel (one ingredient: 12 mg astaxanthin, cold-pressed coconut oil softgel) to your appointment. We can email you a printable version if useful.

Can I take Crocea while pregnant or breastfeeding?

We don't recommend it. Astaxanthin has not been studied in pregnancy or breastfeeding, and there is not enough safety data to recommend its use during these periods.

This isn't because we know of any harm — it's because the studies haven't been done, and the responsible answer in the absence of data is to abstain. Talk to your OB-GYN before adding any new supplement during pregnancy or while nursing.

Can children take Crocea?

Crocea at 12 mg is formulated for adults. We don't recommend it for children under 18.

(There is one published RCT of 4 mg astaxanthin in children aged 10–14 for digital eye strain that showed benefit — but at a lower dose than Crocea's 12 mg, and under physician supervision in a research setting.)

If you're concerned about your child's eye health or screen time, please talk to your paediatrician.

I have surgery scheduled. Should I stop Crocea?

Yes — stop at least 2 weeks before any scheduled surgery, and tell your surgeon you've been taking it.

This is standard precaution for any antioxidant supplement with even mild antiplatelet effects. Surgeons routinely ask patients to stop fish oil, vitamin E, ginkgo, and similar supplements 1–2 weeks before procedures to reduce bleeding risk.

You can resume Crocea after your surgeon clears you, typically a week or two post-op depending on the procedure.

Sourcing & Quality

Where it's grown, how it's tested, and what's on the Certificate of Analysis.

Where exactly is the astaxanthin sourced from?

Our astaxanthin is grown on the Kona coast of the Big Island of Hawaii, in open-air aquaculture ponds. Haematococcus pluvialis algae are cultivated in lava-filtered fresh-water from local aquifers and harvested when their astaxanthin content reaches peak concentration (typically after 5–7 days of intense sunlight stress).

The harvested algae are gently dried and the astaxanthin is extracted using supercritical CO₂ — a solvent-free process that preserves the natural 3S,3'S stereoisomer form (the one studied in clinical trials). The extracted oleoresin is then encapsulated with cold-pressed coconut oil into our softgel.

End-to-end, from algae pond to bottle, the production happens in the USA. We can provide source-and-batch documentation on request.

Is the astaxanthin synthetic or natural?

Natural — from Hawaiian algae. Never synthetic.

Synthetic astaxanthin (produced from petrochemicals) is a different stereoisomer mix and, according to peer-reviewed comparisons, has roughly 20–30× lower biological activity than the natural form. Most cheap astaxanthin supplements use synthetic — it's far less expensive — but the trade-off is that you'd need to take roughly 20–30× the dose to match the same biological effect.

Most farmed Atlantic salmon, by the way, is fed synthetic astaxanthin for colour. That's part of why "just eat more salmon" isn't actually a route to a clinical dose unless you're eating wild sockeye, and even then you'd need about a pound a day.

Is Crocea third-party tested?

Yes. Every production batch is tested by an independent ISO 17025-accredited laboratory for:

  • Potency — actual astaxanthin content matches the 12 mg label claim
  • Heavy metals — lead, mercury, arsenic, cadmium below the strictest USP and California Prop 65 limits
  • Microbials — bacterial and yeast/mould counts within USP specs
  • Identity — confirms the carotenoid is in fact astaxanthin and in the natural 3S,3'S stereoisomer form

We're happy to email the most recent Certificate of Analysis (COA) for any batch — just email support@trycrocea.com with the lot number from your bottle.

What about heavy metals?

Hawaiian-sourced astaxanthin grown in lava-filtered aquifer water has, on independent testing, very low heavy-metal content — significantly below the limits set by USP, California Prop 65, and the European Union.

This is one of the main reasons we chose Hawaiian over open-ocean krill or shellfish sources. Wild marine sources (especially in industrial coastal waters) can bioaccumulate mercury, cadmium, and arsenic in ways that aquifer-fed pond aquaculture does not.

Every batch is tested and the COA is available on request.

Where is Crocea manufactured?

Crocea is manufactured in the USA in cGMP (current Good Manufacturing Practice) certified facilities — the FDA-recognised quality standard for dietary supplements. Every facility we use is audited at least annually by independent third parties.

The astaxanthin oleoresin is produced in Hawaii. Encapsulation and bottling happen at a cGMP-certified contract manufacturer in the continental United States.

Ordering, Payment & Shipping

How to place an order and how it gets to you.

What payment methods do you accept?

All major credit and debit cards (Visa, Mastercard, American Express, Discover), PayPal, Shop Pay, Apple Pay, and Google Pay. International orders may have additional methods at checkout depending on your country.

Payments are processed by Stripe and Shop Pay. We never see or store your full card number — Crocea has no access to your card details beyond what you see on your order confirmation.

Will I be charged sales tax?

Sales tax is calculated at checkout based on your shipping address and applicable state and local tax rates in the US. International orders may be subject to local VAT, GST, or duties depending on your country (these are charged separately by your local authority at delivery and are your responsibility).

Do you offer discounts or promo codes?

Yes:

  • Email subscribers get an introductory discount on their first order — sign up at the footer of any page.
  • Subscription customers save automatically on every shipment.
  • Multi-bottle bundles include a per-bottle discount, shown on the product page.
  • Seasonal promotions are announced by email and on our social channels.

Apply codes at the cart drawer or checkout. Only one code can be used per order — bundle and subscription discounts apply automatically and can't be combined with single-use promo codes.

How long until my order ships?

Orders placed before 2pm ET on a business day typically ship the same day. Orders placed later, or on weekends or US holidays, ship the next business day.

You'll receive a shipping confirmation email with a tracking number as soon as your label is generated. Once handed to the carrier, US delivery is typically 2–7 business days depending on your location.

Full timelines are in our Shipping Policy.

Do you ship internationally?

Yes. We ship to most countries worldwide. Shipping cost and delivery time vary by destination and are calculated at checkout. Typical international transit: 7–14 business days after we ship.

Customs duties, import taxes, and any brokerage fees are charged separately by your local customs authority on delivery and are your responsibility (we have no way to estimate or collect these in advance — they vary by country and order value).

What if my package is lost or arrives damaged?

Email support@trycrocea.com within 14 days of the expected delivery date (or 14 days of receipt for damage) with your order number and, if damaged, a photo of the package and bottle.

We replace lost or damaged orders at no charge — no return required, no investigation period. We'd rather replace your bottle than have you go without.

Subscriptions

How to subscribe, manage, pause, or cancel — all under your control.

How does a Crocea subscription work?

Subscribe & Save on the product page. You choose your frequency (typically every 30 days), enter payment at checkout, and your subscription is active. Each shipment is processed and charged automatically on your chosen schedule.

Subscribing locks in a discount per bottle versus one-time purchase and ensures you never run out — a hidden cost of supplements is missed days while waiting for a re-order. Astaxanthin's benefits depend on consistent daily intake.

Can I cancel my subscription anytime?

Yes, anytime, with no fees and no questions asked. Three ways:

  1. From your account — log in at trycrocea.com, go to Subscriptions, click Cancel.
  2. From any subscription email — every email includes a one-click cancel link. No login required.
  3. Email us at support@trycrocea.com — we'll cancel within one business day.

That's it. No retention scripts, no hoops, no surprise charges after cancellation. Full details in our Subscription Policy.

Can I pause or skip a shipment?

Yes — from your account, you can skip the next shipment, pause for 30/60/90 days, or change your frequency (every 30 / 45 / 60 days). Pause is a great option if you're travelling or have extra bottles stockpiled and don't want to cancel entirely.

Same options if you email support@trycrocea.com — we'll make the change for you.

When am I charged for subscription orders?

Your card is charged on the morning of each scheduled shipment date. Before each charge, you receive an email reminder 3 days in advance with the date, amount, and a link to skip, pause, change, or cancel.

If you need to cancel a specific shipment, you have until the cutoff (typically 24 hours before charge). After that the order is locked for fulfilment.

What if my payment fails?

We'll automatically retry the payment over the next few days and email you to update your card. If the retries fail, the subscription pauses (it doesn't auto-cancel) until you update your payment method.

You can update your card at any time from your account, or by emailing us.

Returns, Refunds & Account

Our 30-Day Satisfaction Guarantee and how to manage your account.

What's your refund policy?

We offer a 30-Day Satisfaction Guarantee on your first order. If Crocea doesn't work for you, email support@trycrocea.com within 30 days of delivery for a full refund of the product price.

Unopened bottles can be returned for a full refund within 30 days. For opened bottles, no physical return is required — we'd rather you don't pay to ship back a bottle you've already tried.

Full details, including how to start a return, exceptions, and refund timing, are in our Refund & Return Policy.

How long does a refund take to process?

Once approved, refunds are issued to your original payment method within 10 business days. Depending on your bank or card issuer, the actual posting to your statement can take an additional 3–5 business days after that.

For PayPal refunds, posting is usually same-day.

How do I update my account, address, or password?

Log in to your Crocea account at trycrocea.com → click on your name in the top right → Account Settings. From there you can update your email, password, default shipping address, payment methods, and subscription preferences.

If you've forgotten your password, use the "Forgot password" link on the login page.

How do I delete my account or my data?

Email privacy@trycrocea.com with the subject "Delete my account" and the email address on your account. We'll process the deletion within 30 days and confirm by email when it's done.

Note that we retain certain transaction records (orders, invoices) for the period required by tax and accounting law — typically 7 years — even after account deletion. Personal marketing data and account login data are deleted in full.

Full details on your privacy rights are in our Privacy Policy.

Still have a question?

Email us. A real person on our care team responds to every message — usually within one business day, often within hours.